Boas.
Eu gostava de saber se há algo de concreto que foi alcançado com o FAH.Pergunto isto porque as únicas coisas que vejo sobre o FAH é terem simulado proteinas em alguns nanosegundos.É que o FAH tem milhares de CPU's e GPU's e alem desses resultados das proteínas simuladas muito rapidamente não encontro nada.
Sei que o objectivo é mais aprofundar o conhecimento básico mas vejam o [email protected] estão quase a desenvolver um medicamento para combater várias estirpes da gripe(se tudo correr bem é claro).
http://boinc.bakerlab.org/rosetta/forum_thread.php?id=1177&nowrap=true#70008
"In a previous post I described the design of small proteins which bind to and block the function of the key surface protein on the influenza virus, called the haemagluttinin (I can never spell that right!). We are very excited about the possibility of making more proteins that bind to the various strains of the virus that could serve as anti flu drugs (this would only be for very acute infections as you probably wouldn't want to take a dose of these too many times) and are actively working on this. Meanwhile, a manuscript describing the design of the first proteins and how they block the haemaglutinin from the Spanish Flu influenza virus has just been accepted as a full research article in Science magazine. We are excited (and nervous) because we've never been this close to making an actual drug before (as I've explained before, most of what we do is directed more at basic understanding than actual drug development). Still, of course, it is a long road (clinical trials, etc if we get that far) to get something to the point it can be used as a drug. I'll keep you posted as we move along with this."
Se eu for ver outros projectos do BOINC encontro várias coisas como "encontramos compostos que conseguem efectivamente reprimir células da doença X".
Então existem alguns resultados mais tangiveis do que uma proteina foldada muito rapidamente??
Eu gostava de saber se há algo de concreto que foi alcançado com o FAH.Pergunto isto porque as únicas coisas que vejo sobre o FAH é terem simulado proteinas em alguns nanosegundos.É que o FAH tem milhares de CPU's e GPU's e alem desses resultados das proteínas simuladas muito rapidamente não encontro nada.
Sei que o objectivo é mais aprofundar o conhecimento básico mas vejam o [email protected] estão quase a desenvolver um medicamento para combater várias estirpes da gripe(se tudo correr bem é claro).
http://boinc.bakerlab.org/rosetta/forum_thread.php?id=1177&nowrap=true#70008
"In a previous post I described the design of small proteins which bind to and block the function of the key surface protein on the influenza virus, called the haemagluttinin (I can never spell that right!). We are very excited about the possibility of making more proteins that bind to the various strains of the virus that could serve as anti flu drugs (this would only be for very acute infections as you probably wouldn't want to take a dose of these too many times) and are actively working on this. Meanwhile, a manuscript describing the design of the first proteins and how they block the haemaglutinin from the Spanish Flu influenza virus has just been accepted as a full research article in Science magazine. We are excited (and nervous) because we've never been this close to making an actual drug before (as I've explained before, most of what we do is directed more at basic understanding than actual drug development). Still, of course, it is a long road (clinical trials, etc if we get that far) to get something to the point it can be used as a drug. I'll keep you posted as we move along with this."
Se eu for ver outros projectos do BOINC encontro várias coisas como "encontramos compostos que conseguem efectivamente reprimir células da doença X".
Então existem alguns resultados mais tangiveis do que uma proteina foldada muito rapidamente??
